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Objective:To investigate the distribution of iron deposition in the substantia nigral (SN) subregions on quantitative susceptibility mapping (QSM) and the change of swallow tail sign (STS) in patients with relapsing-remitting multiple sclerosis (RRMS) of different disease stages.Methods:The clinical and imaging data of 53 patients with RRMS (case group) diagnosed at the First Hospital of Chongqing Medical University from November 2019 to December 2021 were retrospectively analyzed. The case group was divided into 0-5 years subgroup, 6-10 years subgroup, and >10 years subgroup according to the disease duration; another 37 age-and gender-matched healthy volunteers were recruited as the control group during the same period. All subjects underwent MRI and QSM reconstruction. First, the SN was divided into four subregions: rostral anterior-SN (aSNr), rostral posterior-SN (pSNr), caudal anterior-SN (aSNc), and caudal posterior-SN (pSNc) on the QSM, and the quantitative susceptibility value (QSV) of each subregion was measured, and then the STS of the SN was observed and scored on the susceptibility weighted imaging (SWI) generated by post-processing. ANOVA was used to compare the differences in the QSV of each subregion of SN among the groups, and the probability of abnormal STS was compared using the χ 2 test. Spearman′s test was used to analyze the correlation between the QSV of each subregion of SN and the STS score. Results:The differences in QSV of aSNr, pSNr, aSNc, and pSNc were statistically significant among the 0-5 years subgroup, 6-10 years subgroup,>10 years subgroup of RRMS patients and the control group ( P<0.05). The QSV of aSNr, pSNr, and aSNc in 0-5 years subgroup was higher than those in the control group ( P was 0.039, 0.008, 0.039, respectively). The QSV of aSNr, aSNc, and pSNc in the 6-10 years subgroup were higher than those in the 0-5 years subgroup ( P was <0.001, 0.020, 0.015, respectively). The QSV of the aSNc, pSNc in >10 years subgroup were lower than those in the 6-10 years subgroup ( P=0.037, 0.006). The QSV of aSNr, pSNr in >10 years subgroup were higher than those in the control group ( P was <0.001, 0.001). There were 7 cases of abnormal STS in the 0-5 years subgroup, 11 cases in the 6-10 years subgroup, 12 cases in >10 years subgroup, and 9 cases in the control subgroup, and there was a statistically significant difference in the probability of abnormal STS among the subgroups of the RRMS patients and the control subgroup (χ 2=16.20, P=0.011). Both the scores of STS in the 6-10 years subgroup and >10 years group were positively correlated with the QSV in pSNc ( r s=0.65, P=0.006; r s=0.48, P=0.045). Conclusions:In RRMS patients, SN iron deposition is concentrated on aSNr, pSNr, and aSNc in the 0-5 years subgroup and on aSNr, aSNc and pSNc in the 6-10 years subgroup. The QSVs of all SN subregions have a downward trend in >10 years subgroup compared with that in the 6-10 years subgroup. Both the QSVs of the pSNc in the 6-10 years group and >10 years group are positively related to STS scores. These help explore the potential progression pattern of SN iron deposition in RRMS patients and the cause of abnormal STS in RRMS patients.
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OBJECTIVE@#To observe the effect of acupuncture combined with regular treatment and swallowing function training on pharyngeal motor, sensory function and penetration-aspiration function in patients with dysphagia after stroke.@*METHODS@#A total of 60 patients with dysphagia after stroke were randomly divided into a control group and an observation group, 30 patients in each group. Both groups were treated with conventional treatment and swallowing function training; in addition, the observation group was treated with acupuncture at Lianquan (CV 23), Fengfu (GV 16), Yifeng (TE 17). All the treatments were given once a day, 5 days a week, for totally 4 weeks. In the two groups, the pharyngeal motor and sensory function, penetration-aspiration scores were evaluated by fiberoptic endoscopic evaluation of swallowing (FEES), and the Kubota water swallowing test scores were assessed before and after treatment, and the clinical effects were compared.@*RESULTS@#After treatment, the pharyngeal motor and sensory function in the two groups were all higher than those before treatment (P<0.05), and those in the observation group were better than the control group (P<0.05). After treatment, the penetration-aspiration scores and Kubota water swallowing test scores in the two groups were all lower than those before treatment (P<0.05), and those in the observation group were lower than the control group (P<0.05). The total effective rate was 93.3% (28/30) in the observation group, which was better than 73.3% (22/30) in the control group (P<0.05).@*CONCLUSION@#Acupuncture combined with regular treatment and swallowing training could improve the pharyngeal motor and sensory function, and penetration-aspiration scores in patients with dysphagia after stroke.
Subject(s)
Humans , Acupuncture Points , Acupuncture Therapy , Deglutition , Deglutition Disorders/therapy , Stroke/complications , Treatment Outcome , WaterABSTRACT
Abstract Breeding colonies of Storm-petrels (family Hydrobatidae) are poorly known and can be difficult to find because they typically nest on islands in crevices and burrows inside caves. In the past decade, some breeding locations of the Wedge-rumped Storm-petrel (Hydrobates tethys kelsalli) have been reported on islands off central Peru and northern Chile. Here we report the northernmost breeding colony of this subspecies from Isla Foca, northern of Peru. In April 2006 we found 28 nests, of which 46% had chicks and 54% had eggs. Nests consisted of small holes in the rock with no nest material used for construction. Nesting season coincided with that of other reproductive zones found on the Peruvian coast. These results contribute to the knowledge of the distribution of reproductive colonies of this subspecies on the Peruvian coast.
Resumen Las colonias reproductoras de golondrinas de tempestad son poco conocidas y difíciles de encontrar debido a que estas especies anidan en grietas, madrigueras y dentro de cuevas ubicadas en islas. En la última década, se reportaron algunos sitios de reproducción de Golondrinas de Tempestad Peruana (Hydrobates tethys kelsalli) en islas cercanas al centro de Perú y norte de Chile. En este trabajo se presenta el hallazgo de la colonia reproductora ubicada más al norte de esta subespecie, en la Isla Foca (noroeste peruano). En abril de 2006 se registraron 28 nidos, de los cuales el 46% tenían crías y el 54% huevos. Los nidos consistían en pequeñas hoyos en la roca sin ningún tipo de material para su construcción. La temporada de anidación coincidió con la de otras zonas reproductivas encontradas en la costa peruana. Estos resultados contribuyen al conocimiento de la distribución de las colonias reproductivas de esta subespecie en la costa peruana.
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An appropriate animal model of dysphagia is important for research of the mechanism and treatment. Animal models of dysphagia mainly involve rodents, non-human primates and some other mammals, in which rats and mice are the most commonly used. The diseases mainly reproduced include stroke, amyotrophic lateral sclerosis, Parkinson's disease and oropharyngeal neuromuscular diseases, with dysphagia. The success of modeling mainly depends on the assessment of swallowing function, such as videofluoroscopic swallowing study and electrophysiological examination. No animal model can perfectly represent the clinical and pathological characteristics of dysphagia in humans now. With the development of targeted genetic modification and detection indicators, more reasonable dysphagia models would be reproduced.
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Objective@#To apply repetitive saliva swallowing test and standardized swallowing assessment combined with the volume-viscosity swallow test on patients with acquired brain injury, we aim to identify the potential risks of oral intake during the patients′ recovery stage, and improve the strategy of aspiration prevention.@*Methods@#Totally 142 patients with acquired brain injury were selected as the observation group during November 2016 and November 2017, and 153 patients with acquired brain injury were selected as the control group during October 2015 and October 2016. The control group was assessed by water swallow test, while a combination of the Repetitive Saliva Swallowing Test, the Standardized Swallowing Assessment and Volume-Viscosity Swallow Test was used to assess the observation group till discharging. The detection rate of aspiration risk and the incidence of aspiration pneumonia was compared between the two groups.@*Results@#The detection rate of aspiration risk was 36.6% (52/142) in the observation group and 7.8% (12/153) in the control group, the difference was statistically significant (χ2=35.899, P < 0.05). The incidence of aspiration pneumonia was 1.4% (2/142) in the observation group and 12.4% (19/153) in the control group, the difference was statistically significant (χ2=13.502, P < 0.05).@*Conclusions@#The combined application of the Repetitive Saliva Swallowing Test, the Standardized Swallowing Assessment and the Volume-Viscosity Swallow Test can improve the detection rate of aspiration risk in the acquired-brain-injury patients with suspicious swallowing dysfunction, reduce the incidence of aspiration pneumonia, increase the nursing safety, and improve the health outcomes of neurosurgical patients.
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OBJECTIVE: To explore the value of water swallow test(WST)and simple two-step swallowing provocation test(SSPT)in the diagnosis of aspiration in patients with acute exacerbation of chronic obstructive pulmonary disease. METHODS:87 hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease were recruited from the First Affiliated Hospital of Guangzhou Medical University during the period between December 2014 to December 2015. RESULTS: The number of patients of grade1,2,3,4 and 5 of water swallow test successively were 44,39,4,0 and 0. Patients with positive aspiration by the first-step(water injection of 0.4 mL)and the second-step(water injection of 2.0 m L)were 16 and 0. Patients with positive aspiration by radionuclide imaging was 35. Comparison of radionuclide imaging, the rate of missed diagnosis applying water swallow test was high 37.3%(31/83). Both the water swallow test and simple two-step swallowing provocation test have poor consistency with radionuclide imaging in the diagnosis of aspiration in patients with acute exacerbation of chronic obstructive pulmonary disease(McNemar consistency test P=0.00).CONCLUSION: There is a high rate of missed diagnosis applying water swallow test and simple two-step swallowing provocation test to diagnosis aspiration in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD),and combined use of multiple assessment methods can reduce the missed diagnosis rate of aspiration.
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Objective To apply repetitive saliva swallowing test and standardized swallowing assessment combined with the volume-viscosity swallow test on patients with acquired brain injury, we aim to identify the potential risks of oral intake during the patients′recovery stage, and improve the strategy of aspiration prevention. Methods Totally 142 patients with acquired brain injury were selected as the observation group during November 2016 and November 2017, and 153 patients with acquired brain injury were selected as the control group during October 2015 and October 2016. The control group was assessed by water swallow test, while a combination of the Repetitive Saliva Swallowing Test, the Standardized Swallowing Assessment and Volume-Viscosity Swallow Test was used to assess the observation group till discharging. The detection rate of aspiration risk and the incidence of aspiration pneumonia was compared between the two groups. ResuLts The detection rate of aspiration risk was 36.6% (52/142) in the observation group and 7.8% (12/153) in the control group, the difference was statistically significant (χ2=35.899, P<0.05). The incidence of aspiration pneumonia was 1.4% (2/142) in the observation group and 12.4% (19/153) in the control group, the difference was statistically significant (χ2=13.502, P<0.05). ConcLusions The combined application of the Repetitive Saliva Swallowing Test, the Standardized Swallowing Assessment and the Volume-Viscosity Swallow Test can improve the detection rate of aspiration risk in the acquired- brain- injury patients with suspicious swallowing dysfunction, reduce the incidence of aspiration pneumonia, increase the nursing safety, and improve the health outcomes of neurosurgical patients.
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ABSTRACT Objetive: to identify, in the literature, studies that address the use of motor imagery of swallowing. Methods: a systematic review in SCOPUS databases, Science Direct and Medline, with descriptors and free terms "Motor Imagery"; "Swallow"; "Feeding"; "Stomatognathic System"; "mastication ", "Chew "; "Deglutition "; "Deglutition Disorders "; and "Mental Practice". Original articles using the motor imagery of swallowing were included, while reviews were excluded. For data analysis, at the first and second steps, the reading of titles and abstracts of the studies was carried out. In the third step, all studies that were not excluded were read in full. Results: four manuscripts were selected. The use of motor imagery in the rehabilitation of swallowing shows to be a recent proposal (2014-2015). The sample was reduced and comprised mainly healthy individuals. The EMG of the supra-hyoid muscles was used in two manuscripts. The most used neuroimaging technique was the Near-Infrared Spectroscopy, demonstrating the occurrence of hemodynamic changes during motor imagery and motor execution of swallowing. Conclusion: the motor imagery produces brain response in the motor area of the brain, suggesting that mentalization of actions related to swallowing is effective. However, further studies are needed for the application of this approach in the swallowing rehabilitation.
RESUMO Objetivo: identificar na literatura os estudos que abordem o uso da imagética motora da deglutição. Métodos: uma revisão sistemática nas bases de dados SCOPUS, Science Direct e MedLine, com os descritores e termos livres: "Motor Imagery"; "Swallow"; "Feeding"; "Stomatognathic System"; "Mastication", "Chew"; "Deglutition"; "Deglutition Disorders"; e "Mental Practice". Incluídos artigos originais, com o uso da imagética motora da deglutição. Excluídas as revisões. Para análise dos dados, na primeira e segunda etapas foram realizadas a leitura dos títulos e dos resumos dos estudos. Na terceira etapa, todos os estudos que não foram excluídos foram lidos na íntegra. Resultados: foram selecionados 4 manuscritos. O uso da imagética motora na reabilitação da deglutição suscita ser uma proposta recente (2014 - 2015). A amostra foi reduzida e composta majoritariamente por indivíduos saudáveis. A Eletromiografia dos músculos supra-hioides foi utilizada em dois manuscritos. A técnica de neuroimagem mais utilizada foi o Near-Infrared Spectroscopy, demonstrando a ocorrência de mudanças hemodinâmicas durante a imagética motora e execução motora da deglutição. Conclusão: identificou-se que a imagética motora produz resposta cerebral na área motora do cérebro, sugerindo que a mentalização das ações relacionadas à deglutição é eficaz. No entanto, são necessários novos estudos para aplicação desta abordagem na reabilitação da deglutição.
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OBJECTIVE: This study was conducted to evaluate the influence of supraglottic swallowing maneuver on swallowing kinematics using kinematic analysis of a videofluoroscopic swallowing study (VFSS). METHOD: Twenty healthy volunteers (10 in a young group ( < 40 years) and 10 in an elderly group (≥60 years)), participated in this study. After structured instruction by a skilled physician, the subjects swallowed 5 ml of diluted barium in the neutral position without any swallowing maneuvers, as well as with supraglottic swallow maneuver under digital videofluoroscopy, three times each. Kinematic analysis was conducted by digitization of video files for movements of hyolaryngeal structures, including the hyoid bone, larynx, arytenoid, and epiglottis. We measured the maximum displacements and velocities of the hyolaryngeal structures during swallowing. RESULT: The most remarkable change in supraglottic swallow was the maximum vertical displacement (mm) of the hyoid bone during swallowing in both groups (11.5±3.34–19.7±6.88 in the young group, P=0.009; 13.4±2.13–22.8±5.35 in the elderly group, P < 0.001). For velocity variables, patterns of change differed between the young and elderly groups. In the young group, the maximum vertical velocities of the larynx and arytenoid were decreased (P < 0.05), but in the elderly group, the maximum 2D velocity of hyoid bone, maximum horizontal and 2D velocity of the larynx and maximum horizontal velocity of the arytenoid were increased (P < 0.05). There were no significant differences in changes between the young and elderly groups. CONCLUSION: This study showed that supraglottic swallow could affect hyolaryngeal movements, particularly vertical hyoid movement, during swallowing. Beneficial kinematic changes in supraglottic swallow were more pronounced in the elderly group. Therefore, supraglottic swallow may contribute to swallowing improvement by enhancing hyolaryngeal movements during swallowing, in addition to laryngeal closure.
Subject(s)
Aged , Humans , Barium , Biomechanical Phenomena , Deglutition , Epiglottis , Healthy Volunteers , Hyoid Bone , Larynx , MethodsABSTRACT
OBJECTIVE: This study was conducted to identify the frequency of videofluoroscopic swallow study (VFSS) and characteristics of VFSS findings in the patients diagnosed with aspiration pneumonia. METHOD: We retrospectively reviewed the medical records of 2,885 patients who has been diagnosed with aspiration pneumonia either clinically or radiographically. Overall, 811 patients could not be examined because of medical problems. The rest of the subjects were divided into two groups according to the presence of neurologic deficit. The findings of VFSS were scored using the Penetration-Aspiration Scale (PAS) and Pharyngeal Residue Grade (PRG), and data were analyzed based on descriptive statistics, the χ² test, t-test, ANCOVA and logistic regression. RESULT: A total of 1,267 subjects (43.9%) underwent VFSS. Among patients who could be examined, 61.1% were tested. Only 26.7% of subjects without neurologic deficit underwent VFSS, while 56.5% of the subjects in the other group underwent the procedure. The PAS and PRG scores did not differ significantly between groups. About 32.7% of the findings showed silent aspiration (PAS 8), which difficult to detect by bedside screening tests. CONCLUSION: Subjects with neurologic deficit showed significantly higher test rates than the others. There were no significant differences in VFSS findings between groups. Dysphagia should be evaluated in patients with aspiration pneumonia using precise tools, such as VFSS and fiberoptic endoscopic evaluation of swallowing (FEES), regardless of presence of neurological deficit.
Subject(s)
Humans , Deglutition , Deglutition Disorders , Logistic Models , Mass Screening , Medical Records , Methods , Neurologic Manifestations , Pneumonia, Aspiration , Retrospective StudiesABSTRACT
OBJECTIVE: The inability to propel a bolus of food successfully from the posterior part of the oral cavity to the oropharynx is defined as transfer dysphagia. The present case series describes the varied presentation of transfer dysphagia due to focal dystonia and highlights the importance of early detection by following up on strong suspicions. METHODS: We describe seven cases of transfer dysphagia due to focal dystonia. Transfer dysphagia as a form of focal dystonia may appear as the sole presenting complaint or may present with other forms of focal dystonia. RESULTS: Four out of seven patients had pure transfer dysphagia and had previously been treated for functional dysphagia. A high index of suspicion, barium swallow including videofluoroscopy, associated dystonia in other parts of the body and response to drug therapy with trihexyphenidyl/tetrabenazine helped to confirm the diagnosis. CONCLUSION: Awareness of these clinical presentations among neurologists and non-neurologists can facilitate an early diagnosis and prevent unnecessary investigations.
Subject(s)
Humans , Barium , Deglutition Disorders , Diagnosis , Drug Therapy , Dystonia , Dystonic Disorders , Early Diagnosis , Mouth , OropharynxABSTRACT
OBJECTIVE: This study evaluated the temporal variables of hyolaryngeal movements during normal swallowing using kinematic analysis of the video fluoroscopic swallowing study (VFSS) to present the normal cut-off values of those variables. METHODS: Seventy-five healthy volunteers (17 men, 58 women) without swallowing dysfunctions were recruited to examine the swallowing of 2-ml diluted barium by a VFSS. Kinematic analysis was conducted by digitization of video files for movements of hyolaryngeal structures, including the vocal cords, hyoid bone, and epiglottis during normal swallowing. The time points and duration of hyolaryngeal movements were measured. The time points were the start point, maximal point, and the end point of the LE (Laryngeal Elevation), HE (Hyoid Excursion), and EF (Epiglottic Folding). The durations of LE, HE, and EF were obtained by subtracting the time of the start point from the time of the maximal point. The onset time of LE was defined as the reference time point (0 sec). The upper and lower limits of the 95% confidence interval were adopted as the normal cut-off values for the temporal variables of hyolaryngeal movements after transformation to a normal distribution. If a transformation formula to a normal distribution was not found in a variable, the values of the 2.5–97.5 percentile were adopted. RESULTS: The cut-off values of the maximal and end points of the LE were 0.281 to 0.916 sec, and 0.830 to 2.205 sec, respectively. The cut-off values of the start, maximal and end points of the HE were −0.233 to 0.400 sec, 0.320 to 0.874 sec, and 0.889 to 2.055 sec, respectively. The cut-off values of the start, maximal, and end points of the EF were 0.017 to 0.483 sec, 0.364 to 1.055 sec, and 0.774 to 1.773 sec, respectively. The cut-off values of the duration of LE, HE, and EF were 0.281 to 0.916 sec, 0.258 to 0.767 sec, and 0.255 to 0.787 sec, respectively. CONCLUSION: This study presented the normal cut-off values of temporal variables of hyolaryngeal movements during normal swallowing. This study can serve as a basis for classifying and analyzing the patterns of patients with dysphagia.
Subject(s)
Humans , Male , Barium , Deglutition Disorders , Deglutition , Epiglottis , Healthy Volunteers , Hyoid Bone , Vocal CordsABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of electromyography (EMG) guided point injection at Renying (ST 9) for post-stroke dysphagia caused by bulbar paralysis, and explore effective treatments for improving swallowing function on the basis of conventional medicine and rehabilitation training.</p><p><b>METHODS</b>A total of 60 patients were randomly divided into an observation group and a control group, 30 cases in each one. The conventional drugs combined with rehabilitation training were given in the control group, the treatment was given once every day. Based on the treatment in the control group, the EMG guided point injection at Renying (ST 9) was added in the observation group, three times a week. All the treatment was given for 2 weeks. drinking test score and Toshima Ichiro swallow test score were observed before and after treatment in the two groups, and the effects were assessed.</p><p><b>RESULTS</b>Toshima Ichiro swallow test score increased after treatment in both groups compared with that before treatment, and drinking test score decreased compared with that before treatment (all <0.05), and the change rate in the observation group was significantly better than that in the control group (both <0.05). The total effective rate of swallowing efficacy in the observation group was 93.3% (28/30), and the cured rate was 46.7% (14/30), which were better than 26.7% (8/30) and 3.3% (1/30) in the control group (both <0.05).</p><p><b>CONCLUSION</b>On the basis of conventional drugs and rehabilitation training, the EMG guided point injection at Renying (ST 9) can effectively increase the swallowing function of patients with post-stroke dysphagia caused by bulbar paralysis .</p>
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Objective To investigate the effects of different bolus and swallow patterns on esophageal manometry in patients with gastroesophageal reflux disease by high resolution manometry .Methods Patients with gastroesophageal reflux disease questionnaire score of more than 8 points and positive 24-hour pH monitoring were included in the study .All the patients were detected by liquid swallow ,solid swallow and continuous swallow .The parameters and comprehensive diagnosis were in accordance with the Chicago Standard .Results A total of 42 patients with gastroesophageal reflux disease were enrolled . Compared with the dynamic parameters of liquid swallow ,the residual pressure of upper esophageal sphincter [(11 .07 ± 3 .97 ,5 .29 ± 3 .36)mmHg] decreased ,the distal latency [(6 .28 ± 1 .87 ,8 .98 ± 2 .25)s] ,and lower esophageal sphincter relaxation time [(7 .79 ± 0 .98 ,10 .69 ± 13 .04)s] prolonged significantly (all P<0 .05) .In the comprehensive diagnosis of esophageal motility ,compared with liquid swallow (38 .1% ) , continuous liquid swallow showed a more sensitive positive diagnostic rate of ineffective esophageal motility (IEM) (63 .2% ) ,with a significant difference (P=0 .008) .Compared with that of liquid swallow ,the diagnostic rate (45 .2% ) of IEM by the solid swallow did not differ significantly (P=0 .581) . Among the ineffective contraction ,the rate of failed contraction (44.3% ) of solid swallow was higher than that of liquid swallow (22 .6% ) .Conclusion Solid swallow is more likely to induce severe esophageal hypomotility disorders than liquid swallow.Continuous swallow has more sensitivity in the diagnosis of IEM.Therefore.it can be used as a supplement to routine manometry in patients with eastroesophageal reflux disease.
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Head and neck cancer patients are prone to dysphagia and aspiration, which are usually neglected due to treatment of the cancer itself. However, dysphagia and aspiration could cause malnutrition, dehydration, pneumonia, and moreover, have negative impact on the quality of life, morbidity, and mortality. Due to its multifactorial etiology, thorough clinical and instrumental evaluation are necessary. In managing head and neck cancer patients, it has become very important to identify the possibility of dysphagia and aspiration, and to start management as early as possible.
Subject(s)
Humans , Deglutition Disorders , Deglutition , Dehydration , Head and Neck Neoplasms , Head , Malnutrition , Mortality , Pneumonia , Quality of LifeABSTRACT
OBJECTIVES: To compare the videofluoroscopic findings of patients with suspected oropharyngeal dysphagia with the results of a clinical screening protocol. METHODS: A retrospective observational cohort study was conducted on all consecutive patients with suspected oropharyngeal dysphagia between March 2015 and February 2016 who were assigned to receive a videofluoroscopic assessment of swallowing. All patients were first submitted to videofluoroscopy and then to the clinical assessment of swallowing. The clinical assessment was performed within the first 24 hours after videofluoroscopy. The videofluoroscopy results were analyzed regarding penetration/aspiration using an 8-point multidimensional perceptual scale. The accuracy of the clinical protocol was analyzed using the sensitivity, specificity, likelihood ratios and predictive values. RESULTS: The selected sample consisted of 50 patients. The clinical protocol presented a sensitivity of 50% and specificity of 95%, with an accuracy of 88%. "Cough" and "wet-hoarse" vocal quality after/during swallowing were clinical indicators that appeared to correctly identify the presence of penetration/aspiration risk. CONCLUSION: The clinical protocol used in the present study is a simple, rapid and reliable clinical assessment. Despite the absence of a completely satisfactory result, especially in terms of the sensitivity and positive predictive values, we suggest that lower rates of pneumonia can be achieved using a formal dysphagia screening method.
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Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Deglutition Disorders/diagnostic imaging , Triage/standards , Voice Quality , Fluoroscopy/methods , Clinical Protocols , Retrospective Studies , Risk Factors , Sensitivity and SpecificityABSTRACT
Introdução: Durante a internação hospitalar, os pacientes podem sofrer alterações funcionais, como limitações na ingestão de alimentos por via oral, por isso faz-se necessário o uso de via alternativa de alimentação. O fonoaudiólogo ingressa no atendimento hospitalar em uma equipe multidisciplinar, com a finalidade de prevenir e reduzir complicações, gerenciar a deglutição de maneira segura e eficaz. O objetivo deste estudo foi verificar os benefícios do tratamento fonoaudiológico aos pacientes em uso de via alternativa de alimentação. Métodos: Estudo desenvolvido em um hospital com pacientes internados nas enfermarias e Centro de Tratamento Intensivo. Analisaram-se prontuários de pacientes entre dezoito e noventa anos, em uso de via alternativa de alimentação, e classificou-se quanto ao tempo de internação, patologia de base, justificativa para o uso de via alternativa, ocorrência de pneumonia, evolução e via de alimentação na alta. A amostra dividiu-se em dois grupos, Com Acompanhamento Fonoaudiológico (CAF) e Sem Acompanhamento Fonoaudiológico (SAF). Resultados: A amostra foi composta por 288 prontuários, 32,5% com acompanhamento fonoaudiológico e 67,5% sem acompanhamento. A média de internação do grupo CAF foi maior que do grupo SAF. No CAF, 21,3% evoluíram a óbito e 78,7% tiveram alta hospitalar. No SAF, 47,4% evoluíram a óbito e 52,6% tiveram alta. No CAF, 45,7% receberam alta com via oral exclusiva, enquanto 18,6% do SAF tiveram alta com via oral exclusiva. Conclusão: O acompanhamento fonoaudiológico aumentou o tempo de internação hospitalar quando comparados os grupos, porém evidenciou uma diminuição do percentual de óbitos e aumentou a alta hospitalar com via oral exclusiva (AU)
Introduction: During hospitalization, patients may suffer functional changes, such as limitations in oral food intake, which demand the use of an alternative feeding route. The speech therapist enters the hospital's care in a multidisciplinary team, in order to prevent and reduce complications, to manage swallowing safely and effectively. The aim of this study was to determine the benefits of speech therapy for patients using an alternative feeding route. Methods: A study developed in a hospital with inpatients in the wards and Intensive Care Unit. Medical charts of patients between 18 and 90 years old using alternative feeding route were analyzed and classified as for time of hospitalization, baseline pathology, justification for the use of alternative route, pneumonia, evolution, and feeding route at discharge. The sample was divided in two groups, one with speech therapy (WST) and the other with no speech therapy (NST) follow up. Results: The sample consisted of 288 charts, 32.5% with speech therapy and 67.5% without it. The mean hospitalization rate in the WST group was higher than in the NST group. In the WST, 21.3% patients died and 78.7% were discharged from hospital. In the NST, 47.4% patients died and 52.6% were discharged. In the WST, 45.7% were discharged with exclusive oral route, while 18.6% of the NST were discharged with exclusive oral route. Conclusion: Speech therapy increased hospitalization time when the groups were compared, but it evidenced a decrease in the percentage of deaths and increased hospital discharge with exclusive oral route (AU)
Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Deglutition Disorders/rehabilitation , Enteral Nutrition/adverse effects , Speech Therapy , Cross-Sectional Studies , Treatment OutcomeABSTRACT
Objective To study the effect of nursing-coordination-led multidisciplinary collaboration model in the treatment of patients with post-stroke swallowing disorder. Methods About 120 patients who suffered from post-stroke swallowing disorder were randomly divided into two groups:60 patients in the multidisciplinary collaboration group and 60 patients in the control group. In the latter, the patients were treated with conventional deglutition treatment and rehabilitation care, and those in the former were treated on the multidisciplinary collaboration model. The two groups were compared in terms of swallow function, nutrition and physiologicalsituations before and one month after their treatment. Result The swallow function, nutrition and physiological situation in the collaboration group were significantly better than those of the control group (P<0.05). Conclusion The treatment on the nursing-coordination-led multidisciplinary collaboration can effectively improve the patients' swallow function and their nutrition conditions and alleviate the physiological pressure, which is good for their recovery.
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Objective@#To investigate the feasibility and significance of modified Killian(MK) method in the clinical diagnosis of congenital pyriform sinus fistula(CPSF) by electronic laryngoscopy.@*Methods@#The following examinations were performed for 30 suspected cases of CPSF, including the traditional electronic laryngoscopy, MK examination(modified Killian position+ head rotation+ the Valsalva maneuver), barium swallow X-ray(BSX) and CT , and a prospective comparison among them were done. Patients were divided into two groups according to their age: young age group(≤14 years old) and older age group (>14 years old). The results of MK examination from the patients were analyzed and the positive diagnostic rates (PDR) between groups were compared by using χ2 tests.@*Results@#Sinuses in 20 of 30 patients were depicted from pyriform sinus in BSX, and the PDR was 66.7%(20/30). The PRD of CT was 83.3%(25/30). The presence of air bubbles around the upper lobe of the thyroid gland or at the inferomedial edge of cricothyroid joints, morphological changes of thyroid grand as well as pseudo-fistula formation on lower neck were detected clearly on CT. Comparing to the traditional electronic laryngoscopy, the effect of exposing piriform fossa fistula by MK examination is significant(χ2=17.05, P<0.05), with the PDR of 13.3%(4/30) and 76.7%(23/30) respectively. Nevertheless, comparing to BSX and CT, there were no statistically significant differences in the effect to diagnose CPSF (χ2=0.31, χ2=0.10 respectively, P>0.05). The PDR of MK in older group is significantly higher than younger group(χ2=6.68, P<0.05).@*Conclusions@#MK examination can clearly reveal the hypopharyngeal anatomical structure and detect the sinus of CPSF .It could be a safe, feasible, convenient and economical method as an application in preoperative diagnosis and follow-up examination of clinical suspected CPSF.
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Objective To analyze the effects of different food bolus on esophageal motility in patients with non-obstructive esophageal dyshagia by high-resolution esophageal manometry.Methods From March 2014 to June 2015,48 patients with non-obstructive esophageal dysphagia and 12 healthy volunteers (healthy control group) were enrolled.High-resolution manometry was tested when swallowing liquid food,semisolid food and solid food.The lower esophageal sphincter pressure (LESP),4 second integrated relaxation pressure (4 s IRP),distal contractile integral (DCI),distal latency (DL),and breaks were analyzed.T test was performed for statistical analysis.Results According to the 2014 Chicago classification standard,among 48 patients with dysphagia,esophageal dysmotility was diagnosed in 35 patients (72.9％),while 13 patients (27.1％) had normal esophageal motility,and the most common type of esophageal motility disorder was ineffective esophageal motility (31.2％,15/48).The LESP of the healthy control group was (10.85±3.75) mmHg (1 mmHg=0.133 kPa) and 4 s IRP was (1.90±0.84) mmHg.The LESP of dysphagia group was (12.20 ±8.93) mmHg and 4 s IRP was (3.25± 1.02) mmHg.There was no significant difference in LESP and 4 s IRP between two groups (both P＞0.05).The DCIs of liq(u)id swallows,semisolid swallows and solid swallows of healthy control group were (589.00±292.90),(690.17±52.41) and (808.00±448.53) mmHg · s · cm,respectively,which were significantly lower than those of complete normal group in Chicago classification ((1 346.62 ± 244.83),(1 542.46±231.19) and (1 890.31±363.26) mmHg · s · cm;t=4.76,4.68 and 3.79;all P=0.001).The DL of solid swallows of healthy control group was (7.72± 1.15) s,which was significantly lower than that of complete normal group in Chicago classification ((9.00±1.23) s;t=2.61,P=0.021).The breaks of liquid swallows,semisolid swallows and solid swallows of healthy control group were (2.33 ±1.74),(2.37±1.72) and (1.53± 1.22) cm,respectively,which were higher than those of complete normal group in Chicago classification ((0.58±0.48),(0.52±0.47) and (0.85±0.53) cm),and the differences were statistically significant (t =3.02,3.68 and 2.54,all P ＜ 0.05).Conclusions The most common type of esophageal motility disorder in patients with non-obstructive esophageal dysphagia is ineffective esophageal molitity.When swallowing food,the patients with dysphagia but normal results of esophageal manometry according to Chicago classification require more strength of the esophagus,more complete contraction and longer peristaltic time to swallow food bolus.